Abstract Library

#2207 Circulating Neuroendocrine Gene Transcripts (NETest) Decrease Early after Radical Surgery: Preliminary Results of a Prospective Study

Introduction: Specific biomarkers for predicting response and risk of recurrence after surgery for enteropancreatic neuroendocrine tumours (EP-NETs) are still lacking.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Partelli S

Authors: Partelli S, Kidd M, Muffatti F, Andreasi V, Giannone F,

Keywords: NETest, biomarker, Enteropancreatic Neuroendocrine Tumors, diagnosis, surgery,

#1228 Measurement of Blood Gene Transcripts Defines PRRT Therapeutic Efficacy

Introduction: PRRT is an effective therapy for NETs since the majority over-express SSRs. Typically, well or moderately differentiated NETs (G1/G2) are treated. Imaging and CgA are used to evaluate response but both RECIST criteria and CgA have limitations.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Bodei L

Authors: Bodei L, Paganelli G, Kidd M, Severi S, Lepensky C,

Keywords: Gene transcripts, NETest, neuroendocrine, PRRT,

#930 Distinct Expression of Splicing Variants of the Human MEN1 (Multiple Endocrine Neoplasia Type 1) Gene in Various Pituitary Adenomas

Introduction: MEN1 is an autosomal-dominant tumor syndrome characterized by the occurrence of tumors in multiple endocrine tissues, including parathyroid, enteropancreatic neuroendocrine and anterior pituitary. The MEN1 gene consists of 10 exons transcribed into a 610 a.a. protein. It was reported that heterogeneity of human MEN1 gene transcripts related to variation in their 5’ UTR. Six distinct exsons1 (e1A-e1F) were isolated using RNA from thymus, pancreas and kidney.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Ozawa A

Authors: Ozawa A, Watanabe T, Tosaka M, Yoshimoto Y, Horiguchi K,

Keywords: MEN1, pituitary,